发明授权
- 专利标题： Nucleic acid encoding monocyte chemotactic protein 4
- 专利标题（中）： 核酸编码单核细胞趋化蛋白4
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申请号： US09545894申请日： 2000-04-07
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公开(公告)号： US06673915B1公开(公告)日： 2004-01-06
- 发明人: Andrew D. Luster , Eduardo A. Garcia-Zepeda , Mindy N. Sarafi
- 申请人： Andrew D. Luster , Eduardo A. Garcia-Zepeda , Mindy N. Sarafi
- 主分类号： C12N1519
- IPC分类号： C12N1519
摘要：
Substantially pure nucleic acid molecules encoding the monocyte chemotactic proteins MCP-4 and MCP-5. These molecules and the polypeptides they encode are useful in treating diseases or conditions that: (1) are exacerbated by a local immune response, (2) would benefit from a local immune response, or (3) are caused by infectious agents that gain entry to mammalian cells via the chemokine receptors bound by MCP-4 or MCP-5.