发明授权
- 专利标题： Hydroxylation activated prodrugs
- 专利标题（中）： 羟化活化前药
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申请号： US09633699申请日： 2000-08-07
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公开(公告)号： US06677383B1公开(公告)日： 2004-01-13
- 发明人: Gerard Andrew Potter , Lawrence Hylton Patterson , Michael Danny Burke , Paul Crispin Butler
- 申请人： Gerard Andrew Potter , Lawrence Hylton Patterson , Michael Danny Burke , Paul Crispin Butler
- 优先权： GB9802522 19980206
- 主分类号： A61K3109
- IPC分类号： A61K3109
摘要：
The present invention concerns enzymatic aromatic hydroxylation-activated prodrugs, particularly anti-tumor prodrugs and those which are specifically activated by the hydroxylation activity of the enzyme CYP1B1.
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