发明授权
US06689772B1 3-cyanoquinolines, 3-cyano-1,6-naphthyridines, and 3-cyano-1,7-naphthyridines as protein kinase inhibitors
失效
3-氰基喹啉,3-氰基-1,6-萘啶和3-氰基-1,7-萘啶作为蛋白激酶抑制剂
- 专利标题: 3-cyanoquinolines, 3-cyano-1,6-naphthyridines, and 3-cyano-1,7-naphthyridines as protein kinase inhibitors
- 专利标题(中): 3-氰基喹啉,3-氰基-1,6-萘啶和3-氰基-1,7-萘啶作为蛋白激酶抑制剂
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申请号: US10318213申请日: 2002-12-12
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公开(公告)号: US06689772B1公开(公告)日: 2004-02-10
- 发明人: Diane Harris Boschelli , Yanong Wang , Frank Charles Boschelli , Dan Maarten Berger , Nan Zhang , Dennis William Powell , Fei Ye , Ayako Yamashita , Frenel Fils DeMorin , Biqi Wu , Hwei-Ru Tsou , Elsebe Geraldine Overbeek-Klumpers , Allan Wissner
- 申请人: Diane Harris Boschelli , Yanong Wang , Frank Charles Boschelli , Dan Maarten Berger , Nan Zhang , Dennis William Powell , Fei Ye , Ayako Yamashita , Frenel Fils DeMorin , Biqi Wu , Hwei-Ru Tsou , Elsebe Geraldine Overbeek-Klumpers , Allan Wissner
- 主分类号: A61K3133
- IPC分类号: A61K3133
摘要:
This invention provides compounds of Formula (I), having the structure where T, Z, X, A, R1, R2a, R2b, R2c, R3, R4, and n are defined herein, or a pharmaceutically acceptable salt thereof which are useful as antineoplastic agents and in the treatment of osteoporosis and polycystic kidney disease.
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