A resuscitation device for providing a barrier between a rescuer and a patient requiring mouth-to-mouth resuscitation. This resuscitation device includes an inflatable portion which when inflated extends in the breathing direction between the rescuer and the patient so as to be placed around at least one breathing organ of the victim. An inflation member receives airflow from the rescuer to inflate the inflatable portion. In this resuscitation device, a valve assembly permits airflow from the rescuer to the patient and diverts the exhalation and body fluids of the patient from reaching the rescuer. An additional barrier member can also be provided for shielding the rescuer from the patient.