发明授权
- 专利标题： Hydrate forms of alendronate sodium, processes for manufacture thereof, and pharmaceutical compositions thereof
- 专利标题（中）： 阿仑膦酸钠的水合物形式，其制备方法及其药物组合物
-
申请号： US09898756申请日： 2001-07-03
-
公开(公告)号： US06696601B2公开(公告)日： 2004-02-24
- 发明人: Nina Finkelstein , Ramy Lidor-Hadas , Judith Aronhime
- 申请人： Nina Finkelstein , Ramy Lidor-Hadas , Judith Aronhime
- 主分类号： C07F900
- IPC分类号： C07F900
摘要：
New hydrate forms of alendronate sodium, having water content of between about one and about twelve percent, and processes for their manufacture, are disclosed. New crystalline forms of alendronate sodium B, D, E, F, G and H, and processes for manufacturing them, are also disclosed. These new forms of alendronate sodium are suitable for incorporation into pharmaceutical compositions for combating bone resorption in bone diseases.