发明授权
- 专利标题: Tethered ligands and methods of use
- 专利标题(中): 束缚配体和使用方法
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申请号: US09721908申请日: 2000-11-24
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公开(公告)号: US06699677B1公开(公告)日: 2004-03-02
- 发明人: Thomas J. Schall , Brett Premack , Zhenhua Miao , Zheng Wei
- 申请人: Thomas J. Schall , Brett Premack , Zhenhua Miao , Zheng Wei
- 主分类号: G01N33567
- IPC分类号: G01N33567
摘要:
The invention provides methods, reagents and devices for analysis of receptor ligand interactions, determining the profile of receptor expression in cells and cell populations, and diagnostic and drug screening methods. The invention makes use of immobilized tethered ligand fusion proteins having a ligand domain, a stalk domain, and optionally an immobilization domain.
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