发明授权
US06706710B2 Form of (R)-N-[5-methyl-8-(4-methylpiperazin-1-yl)-1,2,3,4-tetrahydro-2-naphthyl]-4-morpholinobenzamide
失效
（R）-N- [5-甲基-8-（4-甲基哌嗪-1-基）-1,2,3,4-四氢-2-萘基] -4-吗啉代苯甲酰胺
![Form of (R)-N-[5-methyl-8-(4-methylpiperazin-1-yl)-1,2,3,4-tetrahydro-2-naphthyl]-4-morpholinobenzamide](/docs/US/2004-03-16/US06706710B2/abs.jpg.600x600.jpg)
- 专利标题： Form of (R)-N-[5-methyl-8-(4-methylpiperazin-1-yl)-1,2,3,4-tetrahydro-2-naphthyl]-4-morpholinobenzamide
- 专利标题（中）： （R）-N- [5-甲基-8-（4-甲基哌嗪-1-基）-1,2,3,4-四氢-2-萘基] -4-吗啉代苯甲酰胺
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申请号： US10333286申请日： 2003-01-17
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公开(公告)号： US06706710B2公开(公告)日： 2004-03-16
- 发明人: Per-Olov Bergström , Martin Hedberg , Mona Lindström , Erica Ståhle
- 申请人： Per-Olov Bergström , Martin Hedberg , Mona Lindström , Erica Ståhle
- 主分类号： A61K315327
- IPC分类号： A61K315327
![Form of (R)-N-[5-methyl-8-(4-methylpiperazin-1-yl)-1,2,3,4-tetrahydro-2-naphthyl]-4-morpholinobenzamide](/abs-image/US/2004/03/16/US06706710B2/abs.jpg.150x150.jpg)
摘要：
This invention relates to a novel form of a scrotonin h5-HT1B-receptor antagonist, namely a novel form of a salt of (R)-N-[5-methyl-8-(4-methylpiperazin-1-yl)-1,2,2,4-tetrahydro-2-naphtyl]-4-morpholinobenzamide referred to as (R)-N-[5-methyl-8-(4-methylpiperazin-1-yl)-1,2,3,4-tetrahydro-2-naphtyl]-4-morpholinobenzamide monohydrobromide Form A. The invention also relates to processes for preparation of said of Form A, which form has a potential use after suitable pharmaceutical formulation in medical treatment, preferably in CNS disorders, over active bladder or vasospam, or growth control of tumors.
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