发明授权
- 专利标题： E2F activity inhibitory compounds
- 专利标题（中）： E2F活性抑制化合物
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申请号： US09269576申请日： 1999-03-30
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公开(公告)号： US06713449B1公开(公告)日： 2004-03-30
- 发明人: Kenji Shibata , Motoo Yamasaki , Tetsuo Yoshida , Tamio Mizukami
- 申请人： Kenji Shibata , Motoo Yamasaki , Tetsuo Yoshida , Tamio Mizukami
- 优先权： JP8-259432 19960930
- 主分类号： A61K3817
- IPC分类号： A61K3817
摘要：
E2F-inhibiting compounds are represented by the formula: R1—A—R2 wherein A represents a peptide sequence comprising a partial amino acid sequence having at least 12 continuous residues in the sequence of the dimerization region or DNA binding region of the E2F family, which are useful as a therapeutic agent of diseases such as tumor and arteriosclerosis, for which abnormal cellular growth is implicated.