Invention Grant
- Patent Title: Thiazole benzamide derivatives and pharmaceutical compositions for inhibiting cell proliferation
- Patent Title (中): 噻唑苯甲酰胺衍生物和抑制细胞增殖的药物组合物
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Application No.: US10190219Application Date: 2002-07-05
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Publication No.: US06720346B2Publication Date: 2004-04-13
- Inventor: Shao Song Chu , Larry Andrew Alegria , Ted Michael Bleckman , Wesley Kwan Mung Chong , Rohit K. Duvadie , Lin Li , Siegfried Heinz Reich , William Henry Romines, III , Michael B. Wallace , Yi Yang
- Applicant: Shao Song Chu , Larry Andrew Alegria , Ted Michael Bleckman , Wesley Kwan Mung Chong , Rohit K. Duvadie , Lin Li , Siegfried Heinz Reich , William Henry Romines, III , Michael B. Wallace , Yi Yang
- Main IPC: A61K31425
- IPC: A61K31425

Abstract:
Aminothiazole compounds with mono-/di-substituted benzamide are represented by the Formula (I), and their pharmaceutically acceptable salts, pharmaceutically acceptable prodrugs, pharmaceutically active metabolites, and pharmaceutically acceptable salts of said metabolites are described. These agents modulate and/or inhibit the cell proliferation and activity of protein kinases and are useful as pharmaceuticals for treating malignancies and other disorders.
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