发明授权
- 专利标题： Chk1 and uses thereof
- 专利标题（中）： Chk1及其用途
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申请号： US09340264申请日： 1999-06-30
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公开(公告)号： US06723498B1公开(公告)日： 2004-04-20
- 发明人: Andrew W. Shyjan , Mark Williamson , Shengfang Jin
- 申请人： Andrew W. Shyjan , Mark Williamson , Shengfang Jin
- 主分类号： C12Q100
- IPC分类号： C12Q100
摘要：
Increased expression of Chk1 is associated with drug resistance of certain cells (e.g., cancer cells). The invention provides methods for identifying drug resistant cells by measuring the expression or activity of Chk1, methods for identifying modulators of drug resistance, and methods for modulating drug resistance by modulating the expression or activity of Chk1.