发明授权
US06723727B1 Substituted purine derivatives, processes for their preparation, their use, and compositions comprising them
有权
取代的嘌呤衍生物,其制备方法,其用途和包含它们的组合物
- 专利标题: Substituted purine derivatives, processes for their preparation, their use, and compositions comprising them
- 专利标题(中): 取代的嘌呤衍生物,其制备方法,其用途和包含它们的组合物
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申请号: US09594033申请日: 2000-06-15
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公开(公告)号: US06723727B1公开(公告)日: 2004-04-20
- 发明人: Anuschirwan Peyman , Jochen Knolle , Volkmar Wehner , Gerhard Breipohl , Jean-Francois Gourvest , Denis Carniato , Thomas Richard Gadek
- 申请人: Anuschirwan Peyman , Jochen Knolle , Volkmar Wehner , Gerhard Breipohl , Jean-Francois Gourvest , Denis Carniato , Thomas Richard Gadek
- 优先权: DE19653646 19961220
- 主分类号: C07D47334
- IPC分类号: C07D47334
摘要:
The present invention relates to compounds of the formulae I and Ia in which X, Y, W, Wa, G and Ga have the meanings given in the patent claims, and their physiologically tolerable salts and their prodrugs, their preparation, their use, in particular as pharmaceutical active compounds, and pharmaceutical preparations comprising them. The compounds of the formula I are vitronectin receptor antagonists and can be employed, for example, as inhibitors of bone resorption and for the treatment of osteoporosis.
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