- 专利标题： Synthesis of 3,6-dialkyl-5,6-dihydro-4-hydroxy-pyran-2-one
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申请号： US10364547申请日： 2003-02-10
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公开(公告)号： US06743927B2公开(公告)日： 2004-06-01
- 发明人: Michael P. Fleming , Yeun-Kwei Han , Lewis M. Hodges , David A. Johnston , Roger P. Micheli , Kurt Puentener , Chris R. Roberts , Michelangelo Scalone , Mark A. Schwindt , Robert J. Topping
- 申请人： Michael P. Fleming , Yeun-Kwei Han , Lewis M. Hodges , David A. Johnston , Roger P. Micheli , Kurt Puentener , Chris R. Roberts , Michelangelo Scalone , Mark A. Schwindt , Robert J. Topping
- 主分类号： C07D30932
- IPC分类号： C07D30932
摘要：
The present invention relates to a novel process for producing a &dgr;-lactone of the formula: using an acyl halide of the formula: wherein R1, R2 R3 and X are described herein, as well as novel intermediates. In particular, the present invention relates to a process for enantioselectively producing the (R)-&dgr;-lactone.