发明授权
- 专利标题： Heterocyclic compounds and their use as medicines
- 专利标题（中）： 杂环化合物及其作为药物的用途
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申请号： US10111994申请日： 2002-04-30
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公开(公告)号： US06747024B1公开(公告)日： 2004-06-08
- 发明人: Serge Auvin , Pierre-Etienne Chabrier de Lassauniere
- 申请人： Serge Auvin , Pierre-Etienne Chabrier de Lassauniere
- 优先权： FR9913858 19991105; FR0006535 20000523
- 主分类号： C07D40712
- IPC分类号： C07D40712
摘要：
The present invention relates to new heterocyclic derivatives having an inhibitory activity on calpains and/or a trapping activity on reactive oxygen species, of formula in which A, X, Y, R1, R2 and Het represent variable groups. The invention also relates to their preparation methods, the pharmaceutical preparations containing them and their use for therapeutic purposes, in particular as inhibitors of calpains and/or traps of reactive oxygen species, selectively or non-selectively.
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