发明授权
- 专利标题: Topical patch preparation containing a delayed-type hypersensitivity inducer and methods for using the same
- 专利标题(中): 包含延迟型超敏反应诱导剂的局部贴剂制剂及其使用方法
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申请号: US10080526申请日: 2002-02-21
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公开(公告)号: US06761900B2公开(公告)日: 2004-07-13
- 发明人: Jutaro Shudo , Ichiro Mori
- 申请人: Jutaro Shudo , Ichiro Mori
- 主分类号: A61F1302
- IPC分类号: A61F1302
摘要:
Topical patch preparations that contain a delayed-type hypersensitivity inducer, e.g., 1-dichloro-2,4-dinitrobenzene (DNCB), and methods for using the same are provided. The subject topical patch preparations are made up of an adhesive gel composition that is present on a support, where the adhesive gel composition includes the delayed-type hypersensitivity inducer, a water-soluble polymer gel, water and a water holding agent. In using the subject topical patch preparations, the topical patch preparations are applied to a skin surface of a subject and maintained at the site of application for a period of time sufficient for an effective amount of the delayed-type hypersensitivity inducer to be administered to the subject, where this maintenance period typically does not exceed about 60 minutes. The subject invention finds use in a variety of applications where the administration of a delayed-type hypersensitivity inducer is desired, and is particularly suited for use in the treatment of HIV associated disease conditions, e.g., AIDS.