发明授权
US06777387B2 Terminally-branched polymeric linkers containing extension moieties and polymeric conjugates containing the same 失效
含有延伸部分的末端支化聚合物接头和含有它们的聚合物共轭物

  • 专利标题: Terminally-branched polymeric linkers containing extension moieties and polymeric conjugates containing the same
  • 专利标题(中): 含有延伸部分的末端支化聚合物接头和含有它们的聚合物共轭物
  • 申请号: US09823296
    申请日: 2001-03-29
  • 公开(公告)号: US06777387B2
    公开(公告)日: 2004-08-17
  • 发明人: Richard B. GreenwaldYun H. Choe
  • 申请人: Richard B. GreenwaldYun H. Choe
  • 主分类号: A61K3816
  • IPC分类号: A61K3816
Terminally-branched polymeric linkers containing extension moieties and polymeric conjugates containing the same
摘要:
The present invention is directed to polymeric prodrug transport forms and methods of making and using the same. In one preferred aspect, the prodrugs are of the formula: wherein G is a polymeric residue; Z is one of: and B is a residue of a biologically active amine-containing moiety or a hydroxyl-containing moiety.
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