发明授权
- 专利标题: Charge tags and the separation of nucleic acid molecules
- 专利标题(中): 电荷标签和核酸分子的分离
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申请号: US09777430申请日: 2001-02-06
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公开(公告)号: US06780982B2公开(公告)日: 2004-08-24
- 发明人: Victor Lyamichev , Zbigniew Skrzpczynski , Hatim T. Allawi , Sarah R. Wayland , Tsetska Takova , Bruce P. Neri
- 申请人: Victor Lyamichev , Zbigniew Skrzpczynski , Hatim T. Allawi , Sarah R. Wayland , Tsetska Takova , Bruce P. Neri
- 主分类号: C07H2100
- IPC分类号: C07H2100
摘要:
The present invention relates to novel phosphoramidites, including positive and neutrally charged compounds. The present invention also provides charge tags for attachment to materials including solid supports and nucleic acids, wherein the charge tags increase or decrease the net charge of the material. The present invention further provides methods for separating and characterizing molecules based on the charge differentials between modified and unmodified materials.
公开/授权文献
- US20020128465A1 Charge tags and the separation of nucleic acid molecules 公开/授权日:2002-09-12
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