发明授权
US06780994B2 Phthalimido arylpiperazines useful in the treatment of benign prostatic hyperplasia
有权
邻苯二甲酰亚氨基芳基哌嗪可用于治疗良性前列腺增生
- 专利标题： Phthalimido arylpiperazines useful in the treatment of benign prostatic hyperplasia
- 专利标题（中）： 邻苯二甲酰亚氨基芳基哌嗪可用于治疗良性前列腺增生
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申请号： US10207473申请日： 2002-07-29
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公开(公告)号： US06780994B2公开(公告)日： 2004-08-24
- 发明人: Gee-Hong Kuo , William V. Murray , Catherine P. Prouty
- 申请人： Gee-Hong Kuo , William V. Murray , Catherine P. Prouty
- 主分类号： C07D29513
- IPC分类号： C07D29513
摘要：
This invention relates to a series of heterocyclic substituted piperazines of Formula I pharmaceutical compositions containing them and intermediates used in their manufacture. The compounds of the invention selectively inhibit binding to the &agr;-1a adrenergic receptor, a receptor which has been implicated in benign prostatic hyperplasia. As such the compounds are potentially useful in the treatment of this disease.