发明授权
US06790631B1 G protein-coupled receptor up-regulated in prostate cancer and uses thereof
失效
G蛋白偶联受体在前列腺癌中上调及其用途
- 专利标题： G protein-coupled receptor up-regulated in prostate cancer and uses thereof
- 专利标题（中）： G蛋白偶联受体在前列腺癌中上调及其用途
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申请号： US09680728申请日： 2000-10-05
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公开(公告)号： US06790631B1公开(公告)日： 2004-09-14
- 发明人: Arthur B. Raitano , Daniel E. H. Afar , Aya Jakobovits , Mary Faris , Rene S. Hubert , Steve Chappell Mitchell , Douglas C. Saffran
- 申请人： Arthur B. Raitano , Daniel E. H. Afar , Aya Jakobovits , Mary Faris , Rene S. Hubert , Steve Chappell Mitchell , Douglas C. Saffran
- 主分类号： G01M3353
- IPC分类号： G01M3353
摘要：
A novel gene (designated PHOR-1) that is highly over-expressed in prostate and other cancers and its encoded protein are described. PHOR-1 is a G protein-coupled receptor with homology to receptors involved in olfaction. PHOR-1 in normal human tissues is restricted to prostate, and this gene is highly over-expressed in prostate cancer as well as in cancers of the kidney, uterus, cervix, stomach and rectum. Consequently, PHOR-1 provides a diagnostic and/or therapeutic target for prostate cancer.
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