发明授权
- 专利标题： Sulfamato hydroxamic acid metalloprotease inhibitor
- 专利标题（中）： 磺酰胺异羟肟酸金属蛋白酶抑制剂
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申请号： US10262622申请日： 2002-09-30
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公开(公告)号： US06800646B1公开(公告)日： 2004-10-05
- 发明人: Gary A. DeCrescenzo , Joseph G. Rico , Terri L. Boehm , Jeffery N. Carroll , Darren J. Kassab , Deborah A. Mischke , Shashidhar Rao
- 申请人： Gary A. DeCrescenzo , Joseph G. Rico , Terri L. Boehm , Jeffery N. Carroll , Darren J. Kassab , Deborah A. Mischke , Shashidhar Rao
- 主分类号： A61K314545
- IPC分类号： A61K314545
摘要：
A sulfamato hydroxamic acid compound that inter alia inhibits matrix metalloprotease activity is disclosed as are a process for preparing the same, intermediate compounds useful in those syntheses, and a treatment process that comprises administering a contemplated sulfamato hydroxamic acid compound in a MMP enzyme-inhibiting effective amount to a host having a condition associated with pathological matrix metalloprotease activity.