发明授权
US06803204B2 Biologically active alternative form of the IKK&agr; I&kgr;B kinase
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IKKalpha IkappaB激酶的生物活性替代形式
- 专利标题: Biologically active alternative form of the IKK&agr; I&kgr;B kinase
- 专利标题(中): IKKalpha IkappaB激酶的生物活性替代形式
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申请号: US10188937申请日: 2002-07-03
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公开(公告)号: US06803204B2公开(公告)日: 2004-10-12
- 发明人: Kenneth B. Marcu , Margery A. Connelly
- 申请人: Kenneth B. Marcu , Margery A. Connelly
- 主分类号: C12Q148
- IPC分类号: C12Q148
摘要:
The present invention provides isolated I&kgr;B kinases that regulate NF&kgr;B gene transcription that lack both a leucine zipper like &agr;-helix domain and helix-loop-helix domain. Also provided are the amino acid sequences of these kinases and the nucleotide sequence encoding these kinases, and other related protein and nucleic acid molecules.
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