Invention Grant
US06806054B2 Non-endogenous, constitutively activated known G protein-coupled receptors
失效
非内源性,组成型激活的已知G蛋白偶联受体
- Patent Title: Non-endogenous, constitutively activated known G protein-coupled receptors
- Patent Title (中): 非内源性,组成型激活的已知G蛋白偶联受体
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Application No.: US09826509Application Date: 2001-04-05
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Publication No.: US06806054B2Publication Date: 2004-10-19
- Inventor: Karin Lehmann-Bruinsma , Chen W. Liaw , I-Lin Lin
- Applicant: Karin Lehmann-Bruinsma , Chen W. Liaw , I-Lin Lin
- Main IPC: G01N3353
- IPC: G01N3353

Abstract:
The invention disclosed in this patent document relates to transmembrane receptors, more particularly to a human G protein-coupled receptor for which the endogenous ligand is known (“known GPCRs”), and most particularly to mutated (non-endogenous) versions of the known GPCRs for use, most preferably in screening assays for the direct identification of candidate compounds as inverse agonists, agonists and partial agonists.
Public/Granted literature
- US20030204073A1 Non-endogenous, constitutively activated known G protein-coupled receptors Public/Granted day:2003-10-30
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