Invention Grant
- Patent Title: Method of preparing clarithromycin
- Patent Title (中): 克拉霉素的制备方法
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Application No.: US10129419Application Date: 2002-05-01
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Publication No.: US06809188B1Publication Date: 2004-10-26
- Inventor: Kwee-Hyun Suh , Mi-Ra Seong , Nam-Du Kim , Gwan-Sun Lee
- Applicant: Kwee-Hyun Suh , Mi-Ra Seong , Nam-Du Kim , Gwan-Sun Lee
- Priority: KR1999/52371 19991124
- Main IPC: C07H1708
- IPC: C07H1708
Abstract:
Clarithromycin can be easily prepared by reacting erythromycin A N-oxide with a methylating agent to obtain 6-O-methylerythromycin A N-oxide; and treating 6-O-methylerythromycin A N-oxide obtained above with a reducing agent in a high yield.
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