Invention Grant
US06812209B1 Conjugate consisting of an active substance and a non-exogenous native protein
失效
由活性物质和非外源天然蛋白质组成的缀合物
- Patent Title: Conjugate consisting of an active substance and a non-exogenous native protein
- Patent Title (中): 由活性物质和非外源天然蛋白质组成的缀合物
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Application No.: US09640838Application Date: 2000-08-16
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Publication No.: US06812209B1Publication Date: 2004-11-02
- Inventor: Hansjörg Sinn , Hans-Hermann Schrenk , Wolfgang Maier-Borst , Gerd Stehle , Andreas Wunder , Dirk Hoff-Biederbeck , Dieter Ludwig Heene
- Applicant: Hansjörg Sinn , Hans-Hermann Schrenk , Wolfgang Maier-Borst , Gerd Stehle , Andreas Wunder , Dirk Hoff-Biederbeck , Dieter Ludwig Heene
- Priority: DE4433890 19940922
- Main IPC: A61K3800
- IPC: A61K3800
Abstract:
This invention relates to a conjugate which consists of an active substance and a native protein which is not regarded as exogenous and distinguish itself in that an intracellulary cleavable linker is present between the active substance and the protein. In addition, this invention concerns a process for the preparation of such a conjugate and its use.
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