A drive bracket assembly includes a bracket (30) for receiving a disk drive (70) therein, an operating member (40) and a cover (60). The bracket includes first and second side panels (31), a pair of slots (36) is defined in the first and second side panels respectively, for slidably receiving respective screws (80) of the disk drive. An upper hook (34) is outwardly formed on the first side panel. A lower hook (48) is outwardly formed on the operating member. A spring (50) is engaged with the upper hook and the lower hook respectively. The operating member includes a concavity (49) adjoining the slot of the first side panel, for securely receiving one rear screw of the disk drive thereby the disk drive is securely retained in the bracket. The disk drive is withdrawn from the bracket by pressing the operating member to disengage said screw from the concavity.