A fuel cell system comprises a fuel cell stack including stacked power-generating cells, a cooling medium-circulating passage for supplying a cooling medium to the fuel cell stack in a circulating manner to cool the power-generating cells, and a heat exchange means arranged for the cooling medium-circulating passage, for performing a heat exchange treatment for the cooling medium used to cool the power-generating cells, wherein the operation temperature of the fuel cell stack is set to be within a range of 100° C. to 210° C. Accordingly, it is possible to improve durability of the fuel cell system in the high output operation and to easily miniaturize the fuel cell system.