- 专利标题: Chelating systems for use in the delivery of compounds to cells
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申请号: US09234606申请日: 1999-01-21
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公开(公告)号: US06818626B1公开(公告)日: 2004-11-16
- 发明人: Jon A. Wolff , James E. Hagstrom , Sean D. Monahan , Vladimir Budker , Vladimir Trubetskoy , Paul M. Slattum
- 申请人: Jon A. Wolff , James E. Hagstrom , Sean D. Monahan , Vladimir Budker , Vladimir Trubetskoy , Paul M. Slattum
- 主分类号: A61K4800
- IPC分类号: A61K4800
摘要:
Chelator containing compounds are utilized in the delivery of molecules, polymers, nucleic acids and genes to animal cells. At least one chelator such as crown ether is attached to a polymer and then associated with another polymer such as DNA. An ion is then added to the mixture thereby forming condensed DNA. In condensed form and in complex with the chelator, DNA can be delivered to a cell.
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