Ink and fixer compositions for printing on hydrophobic media. The ink compositions include a water soluble dye and a vehicle, the vehicle includes water, a glycol ether, a humectant, and a non-ionic surfactant. The fixer compositions include a fixing agent and a vehicle, the vehicle includes water, a glycol ether, a humectant, and a non-ionic surfactant. Methods of printing on hydrophobic media. The methods include the steps of providing an ink that includes a water soluble dye and a vehicle, the vehicle including water, a glycol ether, a humectant, and a non-ionic surfactant; providing a hydrophobic print medium; and depositing the ink on the hydrophobic print medium. The method of printing may further include steps of applying heat to the hydrophobic print medium during and/or after the ink deposition step. The method of printing may yet further include steps of providing a fixer that includes a fixing agent and a vehicle, the vehicle including water, a glycol ether, a humectant, and a non-ionic surfactant; and depositing the fixer on the hydrophobic print medium before, after, or both before and after the ink is deposited.