发明授权
- 专利标题： Process for the preparation of thiazole intermediate
- 专利标题（中）： 制备噻唑中间体的方法
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申请号： US10309812申请日： 2002-12-05
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公开(公告)号： US06833459B2公开(公告)日： 2004-12-21
- 发明人: Pandurang Balwant Deshpande , Parven Kumar Luthra , Rajesh Vyas , Ramakrishna Kamma
- 申请人： Pandurang Balwant Deshpande , Parven Kumar Luthra , Rajesh Vyas , Ramakrishna Kamma
- 优先权： IN325/MAS/2002 20020426
- 主分类号： C07D27724
- IPC分类号： C07D27724
摘要：
The present invention provides a process for the preparation of 4-methyl-5-formyl-thiazole of the formula (I) which comprises reducing the thiazole ester of the formula (III) to thiazole alcohol of the formula (IV), using sodium borohydride in the presence of AlCl3 in a solvent and oxidising using an oxidizing agent the thiazole alcohol of the formula (IV) to obtain 4-methyl-5-formyl-thiazole of the formula (I).
公开/授权文献
- US20030204095A1 Process for the preparation of thiazole intermediate 公开/授权日：2003-10-30
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