发明授权
US06835730B2 4-heteroparyl-1,4-diazabicyclo[3.2.2]nonane, preparation and therapeutic use thereof
有权
4-杂芳基-1,4-二氮杂双环[3.2.2]壬烷，其制备和治疗用途
![4-heteroparyl-1,4-diazabicyclo[3.2.2]nonane, preparation and therapeutic use thereof](/docs/US/2004-12-28/US06835730B2/abs.jpg.600x600.jpg)
- 专利标题： 4-heteroparyl-1,4-diazabicyclo[3.2.2]nonane, preparation and therapeutic use thereof
- 专利标题（中）： 4-杂芳基-1,4-二氮杂双环[3.2.2]壬烷，其制备和治疗用途
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申请号： US10181870申请日： 2002-09-24
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公开(公告)号： US06835730B2公开(公告)日： 2004-12-28
- 发明人: Frédéric Galli , Samir Jegham , Odile Leclerc , Alistair Lochead , Alain Nedelec
- 申请人： Frédéric Galli , Samir Jegham , Odile Leclerc , Alistair Lochead , Alain Nedelec
- 优先权： FR0001098 20000128
- 主分类号： C07D48708
- IPC分类号： C07D48708
![4-heteroparyl-1,4-diazabicyclo[3.2.2]nonane, preparation and therapeutic use thereof](/abs-image/US/2004/12/28/US06835730B2/abs.jpg.150x150.jpg)
摘要：
Compounds of the general formula (I) in which R1, R2, R3 and R4 each represent a hydrogen or halogen atom or a nitro, amino, trifluoromethyl, cyano, hydroxyl, alkyl or alkoxy group, X represents either a nitrogen atom, in which case Z represents a group of the formula C—R5 or a nitrogen atom, or a group of the formula C—R6, in which case Z represents a nitrogen atom, R5 and R6 each represent a hydrogen or halogen atom or a trifluoromethyl, cyano, hydroxyl, (C1-C6)alkyl or (C1-C6)alkoxy group, and R7 represents a hydrogen atom or a (C1-C6)alkyl group. Use in therapy.
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