发明授权
US06844337B2 1,4-diazabicyclo[3.2.2]nonane-phenylisoxazole derivatives, their preparation and their application in therapeutics
有权
1,4-二氮杂双环[3.2.2]壬烷 - 苯并异恶唑衍生物，其制备及其在治疗中的应用
![1,4-diazabicyclo[3.2.2]nonane-phenylisoxazole derivatives, their preparation and their application in therapeutics](/docs/US/2005-01-18/US06844337B2/abs.jpg.600x600.jpg)
- 专利标题： 1,4-diazabicyclo[3.2.2]nonane-phenylisoxazole derivatives, their preparation and their application in therapeutics
- 专利标题（中）： 1,4-二氮杂双环[3.2.2]壬烷 - 苯并异恶唑衍生物，其制备及其在治疗中的应用
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申请号： US10276647申请日： 2001-05-29
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公开(公告)号： US06844337B2公开(公告)日： 2005-01-18
- 发明人: Frédéric Galli , Odile Leclerc , Alistair Lochead
- 申请人： Frédéric Galli , Odile Leclerc , Alistair Lochead
- 申请人地址： FR Paris
- 专利权人： Sanofi-Synthelabo
- 当前专利权人： Sanofi-Synthelabo
- 当前专利权人地址： FR Paris
- 代理商 Michael D. Alexander
- 国际申请： PCTFR01/01649 WO 20010529
- 国际公布： WO0192259 WO 20011206
- 主分类号： A61K31/551
- IPC分类号： A61K31/551 ; A61P25/00 ; A61P25/08 ; A61P25/14 ; A61P25/16 ; A61P25/18 ; A61P25/24 ; A61P25/28 ; A61P25/32 ; A61P25/34 ; A61P25/36 ; A61P43/00 ; C07D471/08 ; A61K31/55
![1,4-diazabicyclo[3.2.2]nonane-phenylisoxazole derivatives, their preparation and their application in therapeutics](/abs-image/US/2005/01/18/US06844337B2/abs.jpg.150x150.jpg)
摘要：
Compounds corresponding to general formula (I) in which R1, R2, R3, R4 and R5 each represent, independently of one another, a hydrogen or halogen atom or a nitro, amino, trifluoromethyl, trifluoromethoxy, cyano, hydroxy, (C1-C6)alkyl, (C1-C6)alkoxy or phenyl group, it also being possible for two of these substituents in adjacent positions together to represent a methylenedioxy group, and R6 represents a hydrogen atom or a (C1-C6)alkyl group. Application in therapeutics.
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