发明授权
- 专利标题: Process for preparing a trifluoroethoxy-substituted benzoic acid
- 专利标题(中): 制备三氟乙氧基取代的苯甲酸的方法
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申请号: US10296065申请日: 2001-05-23
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公开(公告)号: US06849762B2公开(公告)日: 2005-02-01
- 发明人: Kai Fabian , Steffen Enke , Herbert Tilly
- 申请人: Kai Fabian , Steffen Enke , Herbert Tilly
- 申请人地址: DE Darmstadt
- 专利权人: Merck Patent GmbH
- 当前专利权人: Merck Patent GmbH
- 当前专利权人地址: DE Darmstadt
- 代理机构: Millen White Zelano & Branigan, P.C.
- 优先权: DE10025700 20010523
- 国际申请: PCTEP01/05923 WO 20010523
- 国际公布: WO0190062 WO 20011129
- 主分类号: B01J27/122
- IPC分类号: B01J27/122 ; C07B61/00 ; C07C51/367 ; C07C59/64 ; C07C65/00
摘要:
The invention relates to a method for the production of trifluoroethoxy-substituted benzoic acids, by reaction of a corresponding halogenated benzoic acid with trifluoroethanol in the solvent tetrahydrofuran, in the presence of a base and a copper salt, followed by an acidic work-up.