发明授权
- 专利标题: Immunization for ebola virus infection
- 专利标题(中): 免疫埃博拉病毒感染
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申请号: US09913909申请日: 1998-12-23
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公开(公告)号: US06852324B1公开(公告)日: 2005-02-08
- 发明人: Gary J. Nabel , Anthony Sanchez
- 申请人: Gary J. Nabel , Anthony Sanchez
- 申请人地址: US DC Washington
- 专利权人: The United States of America as represented by the Department of Health and Human Services
- 当前专利权人: The United States of America as represented by the Department of Health and Human Services
- 当前专利权人地址: US DC Washington
- 代理机构: Knobbe, Martens, Olson & Bear, LLP
- 国际申请: PCTUS98/27634 WO 19981223
- 国际公布: WO9932147 WO 19990701
- 主分类号: C07K14/08
- IPC分类号: C07K14/08 ; A61K39/12
摘要:
Ebola virus vaccines comprising nucleic acid molecules encoding Ebola viral proteins are provided. In one embodiment, the nucleic acid molecule encodes the transmembrane form of the viral glycoprotein (GP). In another embodiment, the nucleic acid molecule encodes the secreted form of the viral glycoprotein (sGP). In yet another embodiment, the nucleic acid molecule encodes the viral nucleoprotein (NP). Methods for immunizing a subject against disease caused by infection with Ebola virus are also provided.
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