发明授权
- 专利标题: Glucocorticoid receptor modulators
- 专利标题(中): 糖皮质激素受体调节剂
-
申请号: US10012274申请日: 2001-10-26
-
公开(公告)号: US06852719B2公开(公告)日: 2005-02-08
- 发明人: Kevin K. Liu , Bradley P. Morgan , Ralph P. Robinson
- 申请人: Kevin K. Liu , Bradley P. Morgan , Ralph P. Robinson
- 申请人地址: US NY New York US CT Groton
- 专利权人: Pfizer Inc.,Pfizer Products, Inc.
- 当前专利权人: Pfizer Inc.,Pfizer Products, Inc.
- 当前专利权人地址: US NY New York US CT Groton
- 代理机构: Scully, Scott, Murphy & Presser
- 主分类号: A61K31/4245
- IPC分类号: A61K31/4245 ; A61K31/4439 ; A61K31/454 ; A61K31/5377 ; A61K45/06 ; A61P3/04 ; A61P3/10 ; A61P25/00 ; A61P25/22 ; A61P25/24 ; A61P29/00 ; C07D271/06 ; C07D413/04 ; C07D413/06
摘要:
The present invention provides non-steroidal compounds of Formula I, including prodrugs and pharmaceutically acceptable salts thereof, which are selective modulators (e.g., agonists, partial agonists and antagonists) of a steroid receptor, specifically, the glucocorticoid receptor. The present invention also provides pharmaceutical compositions containing these compounds and methods for using these compounds to treat animals requiring glucocorticoid receptor agonist or antagonist therapy. Glucocorticoid receptor modulators are useful to treat diseases, such as obesity, diabetes, inflammation and others as described below. The present invention also provides processes for preparing these compounds
公开/授权文献
- US20040014741A1 Glucocorticoid receptor modulators 公开/授权日:2004-01-22
信息查询