发明授权
US06855836B2 17-Methylene steroids, process for their production and pharmaceutical compositions that contain these compounds
失效
17-亚甲基类固醇,其制备方法和含有这些化合物的药物组合物
- 专利标题: 17-Methylene steroids, process for their production and pharmaceutical compositions that contain these compounds
- 专利标题(中): 17-亚甲基类固醇,其制备方法和含有这些化合物的药物组合物
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申请号: US09963680申请日: 2001-09-27
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公开(公告)号: US06855836B2公开(公告)日: 2005-02-15
- 发明人: Bernd Menzenbach , Peter Droescher , Walter Elger , Alexander Hillisch , Gunter Kaufmann , Hans-Udo Schweikert , Gerd Muller
- 申请人: Bernd Menzenbach , Peter Droescher , Walter Elger , Alexander Hillisch , Gunter Kaufmann , Hans-Udo Schweikert , Gerd Muller
- 申请人地址: DE Jena
- 专利权人: Jenapharm GmbH & Co. KG
- 当前专利权人: Jenapharm GmbH & Co. KG
- 当前专利权人地址: DE Jena
- 代理机构: Millen, White, Zelano & Branigan, P.C.
- 主分类号: A61K31/56
- IPC分类号: A61K31/56 ; C07J13/00
摘要:
The invention relates to 17-methylene steroids, process for their production and pharmaceutical compositions that contain these compounds.The compounds according to the invention have a hybrid-type profile of action in the sense that they act as inhibitors of 5α-reductase and simultaneously as gestagens. They are therefore suitable for treating diseases that are the result of elevated androgen levels in certain organs and tissues in men and women. Together with other hormonal substances, such as an estrogen, testosterone or a strong androgen, the compounds according to the invention are suitable as contraceptive agents for women and for men.
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