- 专利标题： Substituted polycyclic aryl and heteroaryl pyridones useful for selective inhibition of the coagulation cascade
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申请号： US09574740申请日： 2000-05-18
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公开(公告)号： US06867217B1公开(公告)日： 2005-03-15
- 发明人: Michael S. South , Qingping Zeng , Ashton T. Hamme, II , Melvin L. Rueppel
- 申请人： Michael S. South , Qingping Zeng , Ashton T. Hamme, II , Melvin L. Rueppel
- 申请人地址： US IL Skokie
- 专利权人： Pharmacia Corporation
- 当前专利权人： Pharmacia Corporation
- 当前专利权人地址： US IL Skokie
- 主分类号： C07D213/74
- IPC分类号： C07D213/74 ; C07D213/75 ; C07D213/77 ; C07D215/38 ; C07D401/12 ; C07D417/12 ; C07D521/00 ; A61K31/535 ; A61K31/517 ; C07D401/00 ; C07D417/00 ; C07D453/02
摘要：
The invention relates to substituted polycyclic aryl and heteroaryl pyridone compounds useful as inhibitors of serine proteases of the coagulation cascade and compounds, compositions and methods for anticoagulant therapy for the treatment and prevention of a variety of thrombotic conditions including coronary artery and cerebrovascular diseases.
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