发明授权
- 专利标题: Modular cell culture bioreactor and associated methods
- 专利标题(中): 模块化细胞培养生物反应器及相关方法
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申请号: US10645350申请日: 2003-08-21
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公开(公告)号: US06875605B1公开(公告)日: 2005-04-05
- 发明人: Teng Ma
- 申请人: Teng Ma
- 申请人地址: US FL Tallahassee
- 专利权人: Florida State University Research Foundation, Inc.
- 当前专利权人: Florida State University Research Foundation, Inc.
- 当前专利权人地址: US FL Tallahassee
- 代理机构: Allen, Dyer, Doppelt, Milbrath & Gilchrist , P.A.
- 主分类号: C12N5/02
- IPC分类号: C12N5/02 ; C12N5/077 ; C12N5/0789
摘要:
An apparatus and method for a modular cell culture bioreactor comprises a plurality of chambers for cell culture; at least one reservoir containing a cell support medium; a plurality of conduits fluidly connecting the at least one reservoir with the plurality of chambers; and at least one pump fluidly connected through the plurality of conduits with the at least one reservoir and with the plurality of chambers to pump cell support medium therethrough; wherein each individual chamber of the plurality of chambers includes at least one three-dimensional matrix comprising polyethylene terephthalate, a plurality of channels carrying the cell support medium and having the matrix positioned in fluid communication therebetween, and at least two openings into each the channel, wherein a first the opening is in fluid connection with the pump and a second the opening is in fluid connection with the reservoir.