发明授权
- 专利标题: Glycyrrhizin preparations for transmucosal absorption
- 专利标题(中): 甘草甜素制剂经粘膜吸收
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申请号: US10030058申请日: 2000-07-13
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公开(公告)号: US06890547B1公开(公告)日: 2005-05-10
- 发明人: Kanji Takada , Masahiro Murakami
- 申请人: Kanji Takada , Masahiro Murakami
- 申请人地址: JP Kyoto
- 专利权人: Amato Pharmaceutical Products, Ltd.
- 当前专利权人: Amato Pharmaceutical Products, Ltd.
- 当前专利权人地址: JP Kyoto
- 代理机构: Wenderoth, Lind & Ponack, L.L.P.
- 优先权: JP11202803 19990716
- 国际申请: PCTJP00/04714 WO 20000713
- 国际公布: WO0105406 WO 20010125
- 主分类号: A61K9/00
- IPC分类号: A61K9/00 ; A61K9/20 ; A61K9/48 ; A61K9/52 ; A61P1/02 ; A61P1/16 ; A61P17/00 ; A61P17/14 ; A61P31/18 ; A61P37/08 ; A61F13/02 ; A61F6/06
摘要:
By blending glycyrrhizin with an ester mixture comprising a C6-18 fatty acid glycerol ester with a C6-18 fatty acid macrogol ester, glycyrrhizin can be efficiently absorbed via mucosae, in particular, digestive mucosae to achieve a therapeutically effective plasma glycyrrhizin concentration.
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