A heterogeneous computer system, a heterogeneous input/output system and a data back-up method for the systems. An I/O subsystem A for an open system and an I/O subsystem B for a mainframe are connected by a communication unit. In order to back up data from at least a disk connected to the I/O subsystem B in a MT library system and in order to permit the mainframe to access the data in the I/O subsystem B, the I/O subsystem A includes a table for assigning a vacant memory address in a local subsystem to the memory of the I/O subsystem A for an open system. A request of variable-length record format received from the mainframe is converted into a fixed-length record format for the I/O subsystem B. The disk designated according to the table is accessed, and the data thus obtained is sent to the mainframe and backed up in the back-up system.