发明授权
US06893668B2 Process for isolation of anticancer agent camptothecin from Nothapodytes foetida
失效
从Nothapodytes foetida中分离抗癌剂喜树碱的方法
- 专利标题： Process for isolation of anticancer agent camptothecin from Nothapodytes foetida
- 专利标题（中）： 从Nothapodytes foetida中分离抗癌剂喜树碱的方法
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申请号： US10402149申请日： 2003-03-31
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公开(公告)号： US06893668B2公开(公告)日： 2005-05-17
- 发明人: Santosh Kumar Srivastava , Merajuddin Khan , Suman Preet Singh Khanuja
- 申请人： Santosh Kumar Srivastava , Merajuddin Khan , Suman Preet Singh Khanuja
- 申请人地址： IN New Delhi
- 专利权人： Council of Scientific and Industrial Research
- 当前专利权人： Council of Scientific and Industrial Research
- 当前专利权人地址： IN New Delhi
- 代理机构： Nixon & Vanderhye P.C.
- 主分类号： C07D491/22
- IPC分类号： C07D491/22 ; A61K35/78 ; A61K31/44
摘要：
The present invention relates to an improved and economical process for the isolation of anticancer agent Camptothecin from the twigs and stem of Nothapodytes foetida using hot extraction 20(S) Camptothecin is an alkaloid, which contains a pentacyclic ring system that includes a pyrrolo [3,4-b] quinoline moiety (ring A, B and C), the pyridone ring D and a chiral center at C-20 in ring E.
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