发明授权
US06894151B2 Lithium complexes of N-(1-hydroxymethyl-2,3-dihydroxypropyl)-1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclododecane, their production and use
有权
N-(1-羟甲基-2,3-二羟丙基)-1,4,7-三羧甲基-1,4,7,10-四氮杂环十二烷的锂络合物,其生产和使用
- 专利标题: Lithium complexes of N-(1-hydroxymethyl-2,3-dihydroxypropyl)-1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclododecane, their production and use
- 专利标题(中): N-(1-羟甲基-2,3-二羟丙基)-1,4,7-三羧甲基-1,4,7,10-四氮杂环十二烷的锂络合物,其生产和使用
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申请号: US10013840申请日: 2001-12-13
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公开(公告)号: US06894151B2公开(公告)日: 2005-05-17
- 发明人: Johannes Platzek , Peter Blaszkiewicz , Orlin Petrov , Holger Hoffmann
- 申请人: Johannes Platzek , Peter Blaszkiewicz , Orlin Petrov , Holger Hoffmann
- 申请人地址: DE Berlin
- 专利权人: Shering Aktiengesellschaft
- 当前专利权人: Shering Aktiengesellschaft
- 当前专利权人地址: DE Berlin
- 代理机构: Millen, White, Zelano & Branigan
- 优先权: DE10064467 20001215
- 主分类号: A61K49/00
- IPC分类号: A61K49/00 ; C07D257/02 ; C07F1/02 ; C07F5/00
摘要:
The invention relates to crystalline lithium complexes of N-(1-hydroxymethyl-2,3-dihydroxypropyl)-1,4,7-triscarboxymethyl-1,4,7,10 tetraazacyclododecane, their production and the recovery of the salt-free gadolinium complex of N-(1-hydroxymethyl-2,3-dihydroxypropyl)-1,4,7-triscarboxymethyl-1,4,7,10 tetraazacyclododecane from the latter without the use of ion exchangers.
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