A lockable security cabinet for game controllers of the type used to operate electronic slot and card games in gambling casinos. The cabinet includes multiple key locking doors and key operated control switches to allow access to specific areas and controls of a main cabinet thereof housing the computers and other electronics only by authorized persons having the proper key for reach particular area or control switch. The cabinet is slidably mounted to a locking base which bolts into a recess in a gaming table allowing the main cabinet to also be recessed therein yet slide out in a cantilevered fashion to access the doors and controls. The base includes a side or rear cable locking enclosure allowing access to and disconnecting of ends of cables connected to the game controller only upon unlocking of the base and outward sliding of the main cabinet.