发明授权
US06924278B2 Aroyl-piperazine derivatives, their preparation and their use as tachykinin antagonists
失效
芳酰哌嗪衍生物，它们的制备及其作为速激肽拮抗剂的用途
- 专利标题： Aroyl-piperazine derivatives, their preparation and their use as tachykinin antagonists
- 专利标题（中）： 芳酰哌嗪衍生物，它们的制备及其作为速激肽拮抗剂的用途
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申请号： US10720021申请日： 2003-11-24
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公开(公告)号： US06924278B2公开(公告)日： 2005-08-02
- 发明人: Hiroshi Miyake , Kazuhiko Take , Shinji Shigenaga , Hidenori Azami , Hiroshi Sasaki , Yoshiteru Eikyu , Kazuo Nakai , Junya Ishida , Takashi Manabe , Nobukiyo Konishi , Tadashi Terasaka
- 申请人： Hiroshi Miyake , Kazuhiko Take , Shinji Shigenaga , Hidenori Azami , Hiroshi Sasaki , Yoshiteru Eikyu , Kazuo Nakai , Junya Ishida , Takashi Manabe , Nobukiyo Konishi , Tadashi Terasaka
- 申请人地址： JP Osaka
- 专利权人： Fujisawa Pharmaceutical Co., Ltd.
- 当前专利权人： Fujisawa Pharmaceutical Co., Ltd.
- 当前专利权人地址： JP Osaka
- 代理机构： Oblon, Spivak, McClelland, Maier & Neustadt, P.C.
- 优先权： AUP07359 19970617
- 主分类号： A61K31/496
- IPC分类号： A61K31/496 ; A61K31/5377 ; A61K31/541 ; A61K31/55 ; A61P1/00 ; A61P9/00 ; A61P11/00 ; A61P11/06 ; A61P25/00 ; A61P25/04 ; A61P27/02 ; A61P29/00 ; A61P43/00 ; C07D241/04 ; C07D401/06 ; C07D401/12 ; C07D401/14 ; C07D403/06 ; C07D403/14 ; C07D405/06 ; C07D413/06 ; C07D413/12 ; C07D413/14 ; C07D417/08 ; C07D417/14 ; C07D521/00 ; A61K31/33 ; A61K31/495 ; A61K31/54 ; C07D413/00 ; C07D417/00
摘要：
This invention relates to piperazine derivatives of the formula: wherein each symbol is as defined in the description, and its pharmaceutically acceptable salt, to processes for preparation thereof, to pharmaceutical composition comprising the same, and to a use of the same for treating or preventing Tachykinin-mediated diseases in human being or animals.
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