发明授权
- 专利标题: Tricyclic fused heterocyclic compound, process for preparing it and medicament comprising it
- 专利标题(中): 三环稠合杂环化合物,其制备方法和包含它的药物
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申请号: US10903387申请日: 2004-08-02
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公开(公告)号: US06927221B2公开(公告)日: 2005-08-09
- 发明人: Shigeki Hibi , Yorihisa Hoshino , Tatsuya Yoshiuchi , Kogyoku Shin , Kouichi Kikuchi , Motohiro Soejima , Mutsuko Tabata , Yoshinori Takahashi , Hisashi Shibata , Tetsuya Hirakawa
- 申请人: Shigeki Hibi , Yorihisa Hoshino , Tatsuya Yoshiuchi , Kogyoku Shin , Kouichi Kikuchi , Motohiro Soejima , Mutsuko Tabata , Yoshinori Takahashi , Hisashi Shibata , Tetsuya Hirakawa
- 申请人地址: JP Tokyo
- 专利权人: Eisai Co., Ltd.
- 当前专利权人: Eisai Co., Ltd.
- 当前专利权人地址: JP Tokyo
- 代理机构: Birch, Stewart, Kolasch & Birch, LLP
- 优先权: JP11-352553 19991213
- 主分类号: A61P1/04
- IPC分类号: A61P1/04 ; A61P1/08 ; A61P1/10 ; A61P1/12 ; A61P1/14 ; A61P9/04 ; A61P9/10 ; A61P9/12 ; A61P11/00 ; C07D471/14 ; C07D487/14 ; C07D491/14 ; C07D471/04 ; A61K31/437 ; A61P25/24
摘要:
The present invention provides a novel compound having an excellent corticotrophin-releasing-factor receptor antagonistic activity. That is, it provides a compound represented by the following formula, a pharmacologically acceptable salt thereof or hydrates thereof, wherein R2 is a hydrogen atom, etc.; R3 is a hydrogen atom, etc.; the partial structure - - - represents a single or double bond; M′ represents a hydrogen atom, a halogen atom or a C1-6 alkyl group; R7′ represents a hydrogen atom or a C1-6 alkyl group; and W′ represents a phenyl group, pyridyl group, thienyl group, or furyl group, each being optionally substituted; and a pharmacologically acceptable salt thereof or hydrates thereof.
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