发明授权
- 专利标题: Side-chain halogenated amino dicarboxylic acid derivatives as medicaments for treating cardiovascular diseases
- 专利标题(中): 侧链卤代氨基二羧酸衍生物作为治疗心血管疾病的药物
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申请号: US10469178申请日: 2002-02-22
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公开(公告)号: US06939989B2公开(公告)日: 2005-09-06
- 发明人: Michael Härter , Michael Hahn , Claudia Hirth-Dietrich , Andreas Knorr , Elke Stahl , Johannes-Peter Stasch , Frank Wunder
- 申请人: Michael Härter , Michael Hahn , Claudia Hirth-Dietrich , Andreas Knorr , Elke Stahl , Johannes-Peter Stasch , Frank Wunder
- 申请人地址: DE Leverkusen
- 专利权人: Bayer Aktiengesellschaft
- 当前专利权人: Bayer Aktiengesellschaft
- 当前专利权人地址: DE Leverkusen
- 优先权: DE10109861 20010301
- 国际申请: PCT/EP02/01895 WO 20020222
- 国际公布: WO02/07046 WO 20020912
- 主分类号: A61P1/16
- IPC分类号: A61P1/16 ; A61K31/197 ; A61P7/02 ; A61P9/00 ; A61P9/04 ; A61P9/08 ; A61P9/10 ; A61P9/12 ; A61P11/06 ; A61P13/00 ; A61P13/08 ; A61P13/10 ; A61P15/00 ; A61P15/08 ; A61P15/10 ; A61P25/00 ; A61P25/20 ; A61P25/22 ; A61P25/24 ; A61P25/26 ; A61P25/30 ; A61P27/06 ; C07B61/00 ; C07C227/02 ; C07C229/38 ; C07C63/00
摘要:
Compounds of the general formula (I) wherein R1 represents halogen, R2 represent H or halogen, and R3 represents C3-8-cycloalkyl, C3-8-cycloalkenyl, or optionally substituted phenyl, pharmaceutical compositions containing such material, and methods of using such materials in the treatment of various diseases are disclosed and claimed.