发明授权
- 专利标题： Pyrazole derivative
- 专利标题（中）： 吡唑衍生物
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申请号： US09773736申请日： 2001-02-02
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公开(公告)号： US06958339B2公开(公告)日： 2005-10-25
- 发明人: Hirokazu Kubota , Yasuhiro Yonetoku , Keizo Sugasawa , Masashi Funatsu , Souichirou Kawazoe , Akira Toyoshima , Jun Ishikawa , Makoto Takeuchi
- 申请人： Hirokazu Kubota , Yasuhiro Yonetoku , Keizo Sugasawa , Masashi Funatsu , Souichirou Kawazoe , Akira Toyoshima , Jun Ishikawa , Makoto Takeuchi
- 申请人地址： JP Tokyo
- 专利权人： Astellas Pharma Inc.
- 当前专利权人： Astellas Pharma Inc.
- 当前专利权人地址： JP Tokyo
- 代理机构： Sughrue Mion, PLLC
- 优先权： JPP.9-279093 19971013
- 主分类号： A61K31/4155
- IPC分类号： A61K31/4155 ; A61K31/416 ; A61K31/427 ; A61K31/433 ; A61K31/4439 ; A61K31/538 ; C07D231/12 ; C07D231/14 ; C07D401/12 ; C07D403/12 ; C07D409/04 ; C07D409/12 ; C07D409/14 ; C07D413/02 ; C07D417/02 ; C07D417/04 ; C07D417/12 ; C07D417/14 ; C07D521/00 ; A61K31/415
摘要：
The present invention is directed to drugs, in particular, pyrazole derivatives represented by the following general formula (I) which have a calcium release-activated calcium channel inhibitory effect and medicinal compositions, in particular, calcium release-activated calcium channel inhibitors containing the above compounds as the active ingredient, wherein each substituent is defined in the specification. The present invention also relates to a pharmaceutical composition containing an effective amount of the compound of formula (I) and a pharmaceutically effective carrier.The present invention further relates to methods of treatment of diseases associated with calcium release-activated calcium channels, diseases associated with IL-2 production, and methods of treatment of allergic, inflammatory or auto-immune diseases.
公开/授权文献
- US20010011090A1 Pyrazole derivative 公开/授权日：2001-08-02