发明授权
US06972283B2 Glucopyranosyloxypyrazole derivatives, medicinal compositions containing the same and intermediates in the production thereof
有权
吡喃葡萄糖氧吡唑衍生物,含有该衍生物的药物组合物及其生产中的中间体
- 专利标题: Glucopyranosyloxypyrazole derivatives, medicinal compositions containing the same and intermediates in the production thereof
- 专利标题(中): 吡喃葡萄糖氧吡唑衍生物,含有该衍生物的药物组合物及其生产中的中间体
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申请号: US10759138申请日: 2004-01-20
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公开(公告)号: US06972283B2公开(公告)日: 2005-12-06
- 发明人: Hideki Fujikura , Toshihiro Nishimura , Kenji Katsuno , Masahiro Hiratochi , Akira Iyobe , Minoru Fujioka , Masayuki Isaji
- 申请人: Hideki Fujikura , Toshihiro Nishimura , Kenji Katsuno , Masahiro Hiratochi , Akira Iyobe , Minoru Fujioka , Masayuki Isaji
- 申请人地址: JP Nagano
- 专利权人: Kissei Pharmaceutical Co., Ltd.
- 当前专利权人: Kissei Pharmaceutical Co., Ltd.
- 当前专利权人地址: JP Nagano
- 代理机构: Sughrue Mion, PLLC
- 优先权: JP11-246800 19990831
- 主分类号: A61K31/7056
- IPC分类号: A61K31/7056 ; A61P3/04 ; A61P3/10 ; C07D231/20 ; C07H17/02 ; A61K31/70 ; A61K31/415 ; A61K31/7042 ; C07H17/00
摘要:
The present invention relates to glucopyranosyloxypyrazole derivatives represented by the general formula: wherein R1 represents a hydrogen atom or a lower alkyl group; one of Q1 and T1 represents a group represented by the general formula: while the other represents a lower alkyl group or a halo(lower alkyl) group; and R2 represents a hydrogen atom, a lower alkyl group, a lower alkoxy group, a lower alkylthio group, a halo(lower alkyl) group or a halogen atom, or pharmaceutically acceptable salts thereof, which have an inhibitory activity in human SGLT2 and are useful as agents for the prevention or treatment of diabetes, diabetic complications or obesity, and to pharmaceutical compositions comprising the same and intermediates thereof.
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