发明授权
- 专利标题： Imidazolidinedione derivatives for the treatment of diabetes and other diseases
- 专利标题（中）： 咪唑烷二酮衍生物治疗糖尿病等疾病
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申请号： US10894411申请日： 2004-07-19
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公开(公告)号： US06974826B2公开(公告)日： 2005-12-13
- 发明人: Magnus Pfahl , Catherine Tachdjian , Hussien A. Al-Shamma , Andrea Fanjul , David P. M. Pleynet , Lyle W. Spruce
- 申请人： Magnus Pfahl , Catherine Tachdjian , Hussien A. Al-Shamma , Andrea Fanjul , David P. M. Pleynet , Lyle W. Spruce
- 申请人地址： US DE Wilmington US NJ Raritan
- 专利权人： Incyte San Diego Inc.,Ortho McNeil Pharmaceutical Inc.
- 当前专利权人： Incyte San Diego Inc.,Ortho McNeil Pharmaceutical Inc.
- 当前专利权人地址： US DE Wilmington US NJ Raritan
- 代理机构： Needle & Rosenberg, P.C.
- 主分类号： C07D233/76
- IPC分类号： C07D233/76 ; A61K31/4166 ; A61K31/426 ; A61K31/4439 ; A61K31/4709 ; A61K31/498 ; A61P1/00 ; A61P1/04 ; A61P3/06 ; A61P3/08 ; A61P3/10 ; A61P9/10 ; A61P11/00 ; A61P15/00 ; A61P19/02 ; A61P29/00 ; A61P35/00 ; A61P35/02 ; C07D233/40 ; C07D233/42 ; C07D233/86 ; C07D233/96 ; C07D261/12 ; C07D277/20 ; C07D277/34 ; C07D277/36 ; C07D401/06 ; C07D401/10 ; C07D403/10 ; C07D405/10 ; C07D417/06 ; C07D417/10 ; A61K31/44 ; A61K31/415 ; C07D233/28 ; C07D261/04 ; C07D401/00
摘要：
The present invention relates to certain substituted heterocycles of Formula (I) which are useful in the treatment of diseases related to lipid and carbohydrate metabolism, such as type 2 diabetes, adipocyte differentiation, uncontrolled proliferation, such as lymphoma, Hodgkin's Disease, leukemia, breast cancer, prostate cancer or cancers in general; and inflammation, such as osteoarthritis, rheumatoid arthritis, Crohn's Disease or Inflammatory Bowel Disease.