发明授权
US06974838B2 Methods of treating or preventing pain using sibutramine metabolites
有权
使用西布曲明代谢物治疗或预防疼痛的方法
- 专利标题: Methods of treating or preventing pain using sibutramine metabolites
- 专利标题(中): 使用西布曲明代谢物治疗或预防疼痛的方法
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申请号: US10806415申请日: 2004-03-23
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公开(公告)号: US06974838B2公开(公告)日: 2005-12-13
- 发明人: Chrisantha Hugh Senanayake , Qun Kevin Fang , Zhengxu Han , Dhileepkumar Krishnamurthy
- 申请人: Chrisantha Hugh Senanayake , Qun Kevin Fang , Zhengxu Han , Dhileepkumar Krishnamurthy
- 申请人地址: US MA Marlborough
- 专利权人: Sepracor Inc.
- 当前专利权人: Sepracor Inc.
- 当前专利权人地址: US MA Marlborough
- 代理机构: Jones Day
- 主分类号: A61B6/00
- IPC分类号: A61B6/00 ; A61B6/02 ; A61K31/11 ; A61K31/135 ; A61K31/137 ; A61K45/06 ; A61K31/22
摘要:
Methods of making and using racemic and optically pure metabolites of sibutramine, and pharmaceutically acceptable salts, solvates, and clathrates thereof, are disclosed. Pharmaceutical compositions and dosage forms are also disclosed which comprise a dopamine reuptake inhibitor, such as a racemic or optically pure sibutramine metabolite, and optionally an additional pharmacologically active compound.