发明授权
- 专利标题: Gamma-secretase inhibitors
- 专利标题(中): γ-分泌酶抑制剂
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申请号: US10257058申请日: 2001-04-04
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公开(公告)号: US06984626B2公开(公告)日: 2006-01-10
- 发明人: Alan John Nadin , Graeme Irvine Stevenson
- 申请人: Alan John Nadin , Graeme Irvine Stevenson
- 申请人地址: GB Hoddesdon
- 专利权人: Merck, Sharp & Dohme Ltd.
- 当前专利权人: Merck, Sharp & Dohme Ltd.
- 当前专利权人地址: GB Hoddesdon
- 代理商 John C. Todaro; Melvin Winokur
- 优先权: GB0008710 20000407
- 国际申请: PCT/GB01/01549 WO 20010404
- 国际公布: WO01/77144 WO 20011018
- 主分类号: A61K38/06
- IPC分类号: A61K38/06 ; A61K38/05 ; C07K5/04 ; C07K5/06
摘要:
A class of compounds is disclosed which are diasteroisomers of a known class of protease inhibitors. The compound inhibit gamma-secretase, and find use in the treatment of and/or prevention of Alzheimer's disease.
公开/授权文献
- US20030100512A1 Gamma-secretase inhibitors 公开/授权日:2003-05-29
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