发明授权
- 专利标题: Method and apparatus for enhanced size reduction of particles using supercritical fluid liquefaction of materials
- 专利标题(中): 使用超临界流体物质液化来增强颗粒尺寸减小的方法和装置
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申请号: US10932559申请日: 2004-09-02
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公开(公告)号: US06986846B2公开(公告)日: 2006-01-17
- 发明人: Boris Y. Shekunov , Pratibhash Chattopadhyay , Jeffrey S. Seitzinger
- 申请人: Boris Y. Shekunov , Pratibhash Chattopadhyay , Jeffrey S. Seitzinger
- 申请人地址: US OH Cleveland
- 专利权人: Ferro Corporation
- 当前专利权人: Ferro Corporation
- 当前专利权人地址: US OH Cleveland
- 代理机构: Rankin, Hill, Porter & Clark LLP
- 主分类号: B01D11/02
- IPC分类号: B01D11/02 ; A61K9/14
摘要:
The present invention provides a method and an apparatus for forming particles using supercritical fluid. The method includes the steps of mixing a load material with a first flow of a supercritical fluid in a first mixing chamber having a primary mixing device disposed therein to form a melt, transferring the melt from the first mixing chamber to a second mixing chamber having a secondary mixing device disposed therein, mixing the melt with a second flow of the supercritical fluid in the second mixing chamber to form a lower viscosity melt, expanding the lower viscosity melt across a pressure drop into an expansion chamber that is at a pressure below the critical pressure of the supercritical fluid to convert the supercritical fluid to a gas and thereby precipitate the load material in the form of particles.
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